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Effexor xr may interact with other medicines that make you sleepy such as cold or allergy medicines, sedatives, narcotics, sleeping pills, muscle relaxers, and medicines for seizures or anxiety , nonsteroidal anti-inflammatory drugs nsaids , cimetidine, ketoconazole, linezolid, lithium, haloperidol, tramadol, l-tryptophan, warfarin, almotriptan, frovatriptan, sumatriptan, naratriptan, rizatriptan, zolmitriptan, other antidepressants, or other drugs.

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The most commonly observed adverse reactions in the clinical study database in effexor xr treated patients in mdd, gad, sad, and pd incidence 5 and at least twice the rate of placebo were nausea 30.

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Placebo-controlled trials for gad, the following were also common events leading to discontinuation and were considered to be drug-related for effexor xr-treated patients effexor xr n 476 , placebo n 201 headache 4 , 1 ; vasodilatation 1 , 0 ; anorexia 2 , 1 ; dizziness 4 , 1 ; thinking abnormal 1 , 0 ; and abnormal vision 1 , 0 .

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